Contract 75A50118C00015

Spero Therapeutics, Inc. · Department Of Health And Human Services · September 28, 2022

Cost SharingFull & Open CompetitionNAICS 541714

Spero Therapeutics, Inc. was awarded a federal contract by Department Of Health And Human Services (Office Of Assistant Secretary For Preparedness And Response) on September 28, 2022 for $24.13 million of work in research and development in biotechnology (except nanobiotechnology). Performance is in Cambridge, MA. It was awarded under full and open competition. The contract has been modified 4 times since the base award It uses cost sharing contract pricing. The most recent modification was on September 4, 2025. If all options are exercised, the contract could reach $49.73 million.

Obligated to date
$24.13M
$24,133,689
Current value
$49.73M
Modifications
4
Latest September 4, 2025

Contract details

PIID
75A50118C00015
Award type
Definitive Contract
Pricing
Cost Sharing
Set-aside
No Set Aside Used.
Competition
Full And Open Competition
NAICS
541714 · Research And Development In Biotechnology (Except Nanobiotechnology)
Product / service
Health R&D Services; Health Care Services; Experimental Development
Place of performance
Cambridge, MA
First action
September 28, 2022
Latest action
September 4, 2025

Description

MODIFICATION P00021 THIS MODIFICATION IS BEING ISSUED TO DE-OBLIGATE CANCELLING FUNDS IN THE AMOUNT OF $61,887.86.

Modification timeline

  • September 4, 2025
    Mod P00021 · Supplemental Agreement For Work Within Scope
    $49.73M
  • July 14, 2025
    Mod P00020 · Other Administrative Action
    MODIFICATION P00020 THE PURPOSE OF THIS BILATERAL MODIFICATION IS TO: A) UPDATE ARTICLE G.2. CONTRACTING OFFICER?S REPRESENTATIVE (COR).
    $49.80M
  • July 23, 2024
    Mod P00016 · Other Administrative Action
    MODIFICATION P00016 THE PURPOSE OF THIS UNILATERAL MODIFICATION IS TO: A) CORRECT THE PERIOD OF PERFORMANCE END DATE OF CLIN 0002 TO 12/31/2025 PER THE AGREED CONTRACT TERMS. B) AS A RESULT OF THE FO…
    $43.37M
  • July 3, 2024
    Mod P00015 · Supplemental Agreement For Work Within Scope
    MODIFICATION P00015 THE PURPOSE OF THIS BILATERAL MODIFICATION IS TO: A) INCREASE THE US GOVERNMENT FUNDING FOR CLIN 0005 OPTION 4 FROM $12,498,467 BY $11,697,110 TO $24,195,577 AND THE SPERO COST SH…
    $43.37M
  • September 28, 2022
    Mod P00009 · Funding Only Action
    THIS MOD SHOULD INCLUDE UPDATED SOW, GO/NO-GO MILESTONES, GANTT CHART) CHANGE THE CO FROM KATHY TO JONATHAN GONZALEZ; CHANGE KEY PERSONNEL CMO FROM DAVID TO KAMAL; REFLECT CHANGES TO IPP SYSTEM FOR IN…
    $31.03M

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Frequently asked questions

What is contract 75A50118C00015?

Contract 75A50118C00015 is a federal contract awarded to Spero Therapeutics, Inc. by Department Of Health And Human Services on September 28, 2022 for $24.13 million of work classified under RESEARCH AND DEVELOPMENT IN BIOTECHNOLOGY (EXCEPT NANOBIOTECHNOLOGY). It has been modified 4 times since the base award.

Who won contract 75A50118C00015?

Spero Therapeutics, Inc. won contract 75A50118C00015 from Department Of Health And Human Services.

How much is contract 75A50118C00015 worth?

Contract 75A50118C00015 has obligated $24.13 million to date, with a total potential value of $49.73 million if all options are exercised.